反应条件
1: 92 percent / diethyl ether / Ambient temperature
2: 1.) LDA / 1.) THF, -78 deg C, 2.) -78 deg C to RT, 24 h
3: 71 percent / Me4NOAc / hexamethylphosphoric acid triamide / 17 h / 100 °C
5: LiOH / tetrahydrofuran; H2O / 18 h / Ambient temperature
6: Li, liq. NH3 / ethanol / 0.5 h / -78 °C
View Scheme
参考文献
Kende, Andrew S.; Fujii, Yasuhiro; Mendoza, Jose S.
Journal of the American Chemical Society, 1990 , vol. 112, # 26 p. 9645 - 9646
