反应条件
1: 85 percent / LiAlH4 / tetrahydrofuran / 18 h / Heating 2: 97 percent / CH2Cl2 / 1 h 3: 99 percent / Ph3P, CBr4 / CH2Cl2 / 3 h / Ambient temperature 4: 1.) NaH / 1.) DMF, 2 h, 2.) DMF, RT, 2 h View Scheme
参考文献
Higley; Wilde; Maduskuie; Johnson; Pennev; Billheimer; Robinson; Gillies; Wexler
Journal of Medicinal Chemistry, 1994 , vol. 37, # 21 p. 3511 - 3522
