(S)-2-氨基-3-(4-氟苯基)-2-甲基丙酸合成路线 （共 4 条）
反应条件
1: With sodium hydroxide; (R,R)-N,N'-bis(salicylidene)-1,2-cyclohexanediaminocopper(II) in toluene T=20°C; Alkylation; 12 h; phase transfer catalysis; 2: With hydrogenchloride Hydrolysis;
参考文献
Tetrahedron Letters, , vol. 40, # 33 p. 6105 - 6108
反应条件
1: CsOH / (S,S)-3,4,5-trifluorophenyl-NAS bromide / toluene / 0 °C 2: Acid hydrolysis View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 46, p. S206 - S206
反应条件
1: With sodium hydroxide in N,N-dimethyl-formamide T=20 - 25°C; 2: With hydrogenchloride; water in methanol T=50°C; stereoselective reaction;
参考文献
Synthetic Communications, , vol. 41, # 4 p. 493 - 506
反应条件
Yield given. Multistep reaction;
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 39, # 7.2 p. 1479 - 1485
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 7 p. 1630 - 1636
