(3R,4R)-3-氨基-1-羟基-4-甲基-2-吡咯烷酮合成路线 （共 13 条）
反应条件
1: H2 / Pd/C 2: Dowex 50W-X8 (H+ form) / acetone 3: Et3N 4: NaCNBH3, HCl 5: NaOMe / methanol 6: N-phenylsulfonyl-3-phenyloxaziridine, KN(SiMe3)2 / toluene / -90 °C 7: Me2SO 8: i-Pr2NEt 9: methanol / 55 °C 10: H2 / Pt 11: K2CO3 12: H2 / Pd(OH)2 View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 22 p. 1578 - 1580
反应条件
1: NaCNBH3, HCl 2: NaOMe / methanol 3: N-phenylsulfonyl-3-phenyloxaziridine, KN(SiMe3)2 / toluene / -90 °C 4: Me2SO 5: i-Pr2NEt 6: methanol / 55 °C 7: H2 / Pt 8: K2CO3 9: H2 / Pd(OH)2 View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 22 p. 1578 - 1580
反应条件
1: NaOMe / methanol 2: N-phenylsulfonyl-3-phenyloxaziridine, KN(SiMe3)2 / toluene / -90 °C 3: Me2SO 4: i-Pr2NEt 5: methanol / 55 °C 6: H2 / Pt 7: K2CO3 8: H2 / Pd(OH)2 View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 22 p. 1578 - 1580
