1-(3-溴丙氧基)-4-硝基苯合成路线 （共 16 条）
反应条件
potassium carbonate in acetonitrile T=80°C;
参考文献
Song, Hyeseung; Lee, Yun Suk; Roh, Eun Joo; Seo, Jae Hong; Oh, Kwang-Seok; Lee, Byung Ho; Han, Hogyu; Shin, Kye Jung
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5668 - 5674
反应条件
1: 3-bromopropan-1-ol With sodium t-butanolate in toluene T=0 - 20°C; 0.25 h; Inert atmosphere; 2: (4-nitrophenyl)(phenyl)iodonium triflate in toluene T=0 - 20°C; Inert atmosphere; chemoselective reaction;
参考文献
Ghosh, Raju; Lindstedt, Erik; Jalalian, Nazli; Olofsson, Berit
ChemistryOpen, 2014 , vol. 3, # 2 p. 54 - 57
反应条件
N-bromosuccinmide; triphenylphosphine in dichloromethane Heating;
参考文献
Jin, Yi; Zhou, Zu-Yu; Tian, Wei; Yu, Qiang; Long, Ya-Qiu
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5864 - 5869
反应条件
sodium hydroxide; tetrabutylammomium bromide in toluene 24 h; Heating; Yield given. Yields of byproduct given;
参考文献
Synthesis, , # 11 p. 1069 - 1071
反应条件
1: 41 percent / Na2CO3; KI / acetone / Heating 2: 60 percent / NBS; PPh3 / CH2Cl2 / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5864 - 5869
反应条件
in dimethyl sulfoxide
参考文献
Journal of Pharmaceutical Sciences, , vol. 56, p. 380 - 384
参考文献
Journal of the Chemical Society, , p. 3298,3308
参考文献
Loewe; Urbanietz
Arzneimittel-Forschung, 1965 , vol. 15, # 6 p. 604 - 608
反应条件
1: 67 percent / tetrahydrofuran / 24 h / Heating 2: 95 percent / hydrogen / 10percent palladium-charcoal / methanol / 2 h View Scheme
参考文献
Hooper, Malcolm; Imam, S. Haider
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1583 - 1588
反应条件
(i) NaOEt, EtOH, (ii) aq. KOH, MeOH; Multistep reaction;
参考文献
Collins,R.F.; Davis,M.
Journal of the Chemical Society, 1961 , p. 1863 - 1879
