1: 2.46 g / TFA / CH2Cl2 / 1) 3 min, 0 deg C, 2) 17 min, without cooling 2: 78 percent / pyridine / 1.87 h / 101 °C 3: H2, 0.1N aq.HCl / 10percent Pd-C / methanol / 2.33 h View Scheme

1: 100 percent / trifluoroacetic acid (TFA) / CH2Cl2 2: 91 percent / pyridine / 12 h 3: H2, HCl / 10percent Pd/C / methanol View Scheme

1: 2.46 g / TFA / CH2Cl2 / 1) 3 min, 0 deg C, 2) 17 min, without cooling 2: 78 percent / pyridine / 1.87 h / 101 °C 3: 21 percent / H2, NH3, conc.NH4OH / Raney nickel W-2 / methanol / 3 h / 0 °C / 2947.7 - 3102.9 Torr 4: 54 percent / diphenylphosphoryl azide / dimethylformamide / 96 h / -1 - 8 °C 5: 100 percent / H2 / 10percent Pd-C / methanol / 7 h View Scheme