1: 85 percent / DMAP / acetonitrile / 28 h / Ambient temperature 2: 90 percent / Bu3SnH, 2,2'-azobis(2-methylpropionitrile) / benzene / 0.33 h / Heating 3: 83 percent / aq. AcOH / 1 h / Ambient temperature 4: 1) hydrazine, 2) Raney Ni / 1) 90 min, reflux, 2) aq. EtOH, reflux, 2 h View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 61 percent / KOH, tris-&lt;2-(2-methoxyethoxy)ethyl&gt;amine / acetonitrile / 1 h / Ambient temperature<br />2: 92 percent / methanolic NH₃ / 16 h / Ambient temperature<br />3: 82 percent / AgNO₃, pyridine / tetrahydrofuran / 3.5 h / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 61 percent / KOH, tris-&lt;2-(2-methoxyethoxy)ethyl&gt;amine / acetonitrile / 1 h / Ambient temperature<br />2: 92 percent / methanolic NH₃ / 16 h / Ambient temperature<br />3: 82 percent / AgNO₃, pyridine / tetrahydrofuran / 3.5 h / Ambient temperature<br /> <br /> &nbsp;