1: 1) BH3*Me2S 2) Me3NO / 1) THF, -78 to 25 deg C 2) toluene, 1.5h, reflux 2: 90 percent / n-Bu4NF / tetrahydrofuran / 2 h / 0 to 25 deg C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: DBU / CH₂Cl₂ / 48 h / 24 &deg;C<br />2: 100 percent / LiN(TMS)2 / tetrahydrofuran / -78 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: DBU / CH₂Cl₂ / 24 h / 25 &deg;C<br />2: 100 percent / LiN(TMS)2 / tetrahydrofuran / -78 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '8136861', constants.ctx, '0')">lithium hexamethyldisilazane</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />T=-78&deg;C;&nbsp;<br /> &nbsp;