1: Jone's reagent / acetone / 0 - 4 °C 2: sulfuric acid / 20 °C View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1.1: toluene-4-sulfonic acid / dichloromethane / 20 &deg;C<br />2.1: n-butyllithium / tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane / 0.5 h / -60 &deg;C<br />2.2: -20 - 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: toluene-4-sulfonic acid / dichloromethane / 20 &deg;C<br />2.1: n-butyllithium / tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexane / 0.5 h / -60 &deg;C<br />2.2: -20 - 20 &deg;C<br /> <br /> &nbsp;