2-甲基-9H-1,2,3,4-四氢吡啶并(3,4-b)吲哚合成路线 （共 15 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
1.) room temp., 1 h, 2.) reflux, 3 h;
参考文献
Lehmann, Jochen; Pohl, Ursula
Archiv der Pharmazie (Weinheim, Germany), 1988 , vol. 321, p. 411 - 414
反应条件
sodium tetrahydroborate
参考文献
Booth; Trevor; Singer; Castagnoli Jr.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 2 p. 473 - 477
反应条件
1: 59 percent / ethanol / 48 h / 200 - 210 °C / 30002.4 - 33752.7 Torr
2: 51 percent / LiAlH4 / tetrahydrofuran / 1.) room temp., 1 h, 2.) reflux, 3 h
View Scheme
参考文献
Lehmann, Jochen; Pohl, Ursula
Archiv der Pharmazie (Weinheim, Germany), 1988 , vol. 321, p. 411 - 414
反应条件
formaldehyd; sulfuric acid
参考文献
Juraschewskii
Zhurnal Obshchei Khimii, 1954 , vol. 24, p. 729,732; engl. Ausg. S. 737, 739
反应条件
N-bromosuccinmide; acetic acid in tetrahydrofuran; water
T=20°C; 0.25 h;
参考文献
White, James D.; Li, Yang; Ihle, David C.
Journal of Organic Chemistry, 2010 , vol. 75, # 11 p. 3569 - 3577
