1.1: 4-(N,N-dimethlyamino)pyridine; triethylamine; hydrogen / palladium 10 on activated carbon / tetrahydrofuran / 24 h / 20 °C 2.1: triethylamine; 2-hydroxy-pyridine / tert-butyl methyl ether / 18 h / 80 °C 3.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C 3.2: pH 10 View Scheme

1: 4-(N,N-dimethlyamino)pyridine; triethylamine; hydrogen / palladium 10 on activated carbon / tetrahydrofuran / 24 h / 20 °C 2: triethylamine; 2-hydroxy-pyridine / tert-butyl methyl ether / 18 h / 80 °C View Scheme

4-(N,N-dimethlyamino)pyridine; hydrogen; triethylamine; palladium 10 on activated carbon in tetrahydrofuran T=20°C; 24 h;