1: 1-(3-hydroxyphenyl)propan-1-one With potassium hydroxide in acetone T=40°C; 0.5 h; 2: methyl iodide With tetrabutylammomium bromide; potassium carbonate in acetone T=40 - 45°C; 12 h;

molybdenum(IV) disulfide T=275°C; P=73550.8 Torr; Hydrogenation;

Hydrogenation;

in N-methyl-acetamide

in N-methyl-acetamide

暂无反应条件数据

1.1: hydrogenchloride / isopropyl alcohol; water / 16 h / Reflux 2.1: potassium carbonate / dichloromethane / 1 h / 30 - 35 °C 3.1: (2R,3S)-(-)-di-O-benzoyl tartaric acid / ethyl acetate / 5 h / 10 - 20 °C / Cooling 3.2: 1 h / 20 - 25 °C 4.1: tetrahydrofuran / 3 h / 25 - 30 °C 5.1: hydrogenchloride / water / 24 h / Reflux 5.2: 10 - 15 °C 6.1: hydrogenchloride; hydrogen / palladium 10 on activated carbon / ethanol; water / 36 h / 4413.43 Torr 6.2: 20 °C / pH 7 - 8 7.1: sodium hydroxide; water / methanol / 20 h / 28 - 35 °C 7.2: 5 - 10 °C / pH 10 - 11 View Scheme

nitric acid; acetic acid T=70°C;