反应条件
1.1: potassium carbonate; sodium iodide / acetonitrile / 2 h / Inert atmosphere; Reflux 2.1: trifluoroacetic acid / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere 2.3: -78 - 20 °C 3.1: pyridine / chloroform / Inert atmosphere 4.1: potassium tert-butylate / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 2.5 h / Inert atmosphere; Reflux View Scheme
参考文献
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES; PIERRE FABRE MEDICAMENT; Nicolas, Marc; Larquetoux, Laurent; Leroux, Sébastien; Doris, Eric
Patent: US2013/296553 A1, 2013 ;
