(S)-(+)-2-羟基-2-苯丙酸合成路线 (共 31 条)
反应条件
1: 97 percent / pyridine / benzene / 3 h / Ambient temperature View Scheme
参考文献
Bulletin des Societes Chimiques Belges, , vol. 95, p. 557 - 566
反应条件
1.1: lithium diisopropylamine / hexane; diethyl ether / 0.5 h / -78 °C 1.2: hexane; diethyl ether / 2 h / -78 °C 2.1: aq. KOH / methanol / 3 h / Heating View Scheme
参考文献
Journal of Chemical Research, , # 12 p. 816 - 817
反应条件
1: 1) LiN(i-Pr)2, HMPT 2: H2O / e.e. 70percent View Scheme
参考文献
Tetrahedron Letters, , vol. 22, # 42 p. 4221 - 4224
反应条件
(i), (ii) <Et3O>BF4, (iii) aq. KOH; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 44, # 13 p. 2247 - 2249
反应条件
phosphate buffer pH 7.0 Aspergillus oryzae protease, 6-8 h; Yield given. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 3 p. 653 - 654
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 19, p. 227 - 246
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 25, # 18 p. 1897 - 1900
反应条件
Hydrolyse des Reaktionsprodukts mit alkoholischer Kalilauge;
参考文献
Journal of the Chemical Society, , vol. 89, p. 378
反应条件
partielle asymmetrische Synthese;
参考文献
Journal of the Chemical Society, , p. 3219,3222
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 95, p. 557 - 566