3-[3-(二甲基氨基)丙基]-1H-吲哚合成路线 (共 4 条)
反应条件
lithium aluminium tetrahydride in 1,4-dioxane T=100°C;
参考文献
Celik, Leyla; Sinning, Steffen; Severinsen, Kasper; Hansen, Carsten G.; Moller, Maria S.; Bols, Mikael; Wiborg, Ove; Schiott, Birgit
Journal of the American Chemical Society, 2008 , vol. 130, # 12 p. 3853 - 3865
反应条件
sodium tris(acetoxy)borohydride in tetrahydrofuran
参考文献
Denhart, Derek J.; Mattson, Ronald J.; Ditta, Jonathan L.; Macor, John E.
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3803 - 3805
反应条件
1: (2S,5S)-5-benzyl-2-tert-butyl-3-methyl-imidazolidin-4-one; TFA / propan-2-ol; CH2Cl2 / -25 °C 2: NaBH(OAc)3 / tetrahydrofuran View Scheme
参考文献
Denhart, Derek J.; Mattson, Ronald J.; Ditta, Jonathan L.; Macor, John E.
Tetrahedron Letters, 2004 , vol. 45, # 19 p. 3803 - 3805
反应条件
1: EDC; HOBT; Et3N / dimethylformamide / 20 °C 2: LAH / tetrahydrofuran View Scheme
参考文献
Guan, Huiping; Laird, A. Douglas; Blake, Robert A.; Tang, Cho; Liang, Chris
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 1 p. 187 - 190