sodium hydride; potassium iodide 1.) THF, DMF (1:1), 2.) reflux, 24 h;

1: acetoacetic acid methyl ester With sodium hydride; potassium iodide in tetrahydrofuran; N,N-dimethyl-formamide T=0 - 20°C; 2: 4-pentynyl tosylate in tetrahydrofuran; N,N-dimethyl-formamide T=20 - 100°C;

N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride 1.) THF, -10 deg C, 10 min; room temperature, 1 h, 2.) 50 deg C, 12 h; Yield given. Multistep reaction;

sodium hydride

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