反应条件
1: 90 percent / imidazole / dimethylformamide / 14 h / Ambient temperature 2: 1.) LDA, 2.) p-toluenesulfonyl chloride / 1.) THF, -70 deg C, 1 h, 2.) -70 deg C, 1 h 3: 84 percent / AcOH, H2O / tetrahydrofuran / 14 h / Ambient temperature View Scheme
参考文献
Tanaka; Baba; Hayakawa; Sakamaki; Miyasaka; Ubasawa; Takashima; Sekiya; Nitta; Shigeta; Walker; Balzarini; De Clercq
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 349 - 357
