Boc-L-苯丙氨酰-苯丙氨酸合成路线 （共 18 条）
反应条件
1: 82 percent / Et3N / CH2Cl2 / 20 °C 2: aq. LiOH / methanol / 5 h View Scheme
参考文献
Organic Letters, , vol. 6, # 20 p. 3433 - 3436
反应条件
1: sodium hydroxide / 1,4-dioxane; water / 20 °C / Cooling with ice 2: benzotriazol-1-ol; dicyclohexyl-carbodiimide / dichloromethane / 48 h / 20 °C / Cooling with ice 3: sodium hydroxide / methanol / 10 h View Scheme
参考文献
Soft Matter, , vol. 8, # 20 p. 5621 - 5628
反应条件
1: 65 percent / tyrosinase; phosphate buffer; O2 / H2O; acetonitrile / 6 h / 20 °C / pH 7.0 2: 88 percent / N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; HOBt / CH2Cl2 / 0 - 20 °C 3: 26 percent / tyrosinase; phosphate buffer; O2 / H2O; acetonitrile / 108 h / 20 °C / pH 7.0 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 20 p. 6902 - 6910
反应条件
1: 59.6 percent / IBCF, NMM 2: 93 percent / 1 N NaOH / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 3 p. 179 - 186
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran; water 2 h;
参考文献
Meneses, Celia; Nicoll, Sarah L.; Trembleau, Laurent
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 564 - 569
反应条件
1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran; dichloromethane / 0 °C 1.2: 20 °C 2.1: lithium hydroxide hydrate / methanol; water / 0 - 20 °C View Scheme
参考文献
Polymer, , vol. 53, # 8 p. 1694 - 1702
反应条件
potassium hydroxide in ethanol 1 h; Ambient temperature; Yield given;
参考文献
Liebigs Annalen der Chemie, , p. 331 - 336
反应条件
1: N-tert-butoxycarbonyl-L-phenylalanine With 1-hydroxy-pyrrolidine-2,5-dione; diisopropyl-carbodiimide in chloroform 2 h; 2: L-phenylalanine in water; acetone pH=8 - 9;
参考文献
Chemical Communications, , vol. 47, # 47 p. 12625 - 12627
