N-苄氧羰基-L-苯丙氨酰基-L-苯丙氨酸合成路线 （共 27 条）
反应条件
1.1: 4-methyl-morpholine / tetrahydrofuran / 0.08 h / 20 °C 1.2: 0.17 h / -15 °C 2.1: sodium hydroxide; tetrabutylammomium bromide / water / 0.5 h / 0 °C View Scheme
参考文献
Verardo; Gorassini
Journal of Peptide Science, 2013 , vol. 19, # 5 p. 315 - 324
反应条件
2: aq. NaOH View Scheme
参考文献
Sokotowska,T.; Biernat,J.F.
Roczniki Chemii, 1966 , vol. 40, p. 1665 - 1673
反应条件
Carbonate buffer T=22.5°C; pH 9.5; var. temp., also Z-D-Phe-L-Phe-PMCP;
参考文献
Matsumoto, Yoko; Matsumoto, Yoshito; Inoue, Junichi; Ueoka, Ryuichi
Chemistry Letters, 1993 , # 8 p. 1303 - 1304
反应条件
Multistep reaction; the possibility of the application of the new PetOH protecting group in peptide synthesis was investigated via the rate of racemization;
参考文献
Kessler, Horst; Becker, Guenther; Kogler, Herbert; Wolff, Michael
Tetrahedron Letters, 1984 , vol. 25, # 36 p. 3971 - 3974
反应条件
hydrogenchloride; carboxypeptisae-A in water T=37°C; pH=6.5; Enzyme kineticsKinetics; Further Variations:Reagents;
参考文献
Kanosue, Yoshifumi; Kojima, Satoshi; Hiraga, Yoshikazu; Ohkata, Katsuo
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 6 p. 1187 - 1193
反应条件
1: With chloroformic acid ethyl ester; triethylamine in tetrahydrofuran
T=5°C; 0.5 h;
2: With ammonium chloride in tetrahydrofuran; water
T=5°C; 0.5 h; Time; Overall yield = 63percent;
参考文献
Noguchi, Takuya; Jung, Seunghee; Imai, Nobuyuki
Tetrahedron Letters, 2014 , vol. 55, # 2 p. 394 - 396
反应条件
1: triethylamine / tetrahydrofuran / -15 °C
2: ammonium chloride / tetrahydrofuran; water / 24 h / -15 °C
View Scheme
参考文献
Noguchi, Takuya; Jung, Seunghee; Imai, Nobuyuki
Tetrahedron Letters, 2014 , vol. 55, # 2 p. 394 - 396
