N-皮丁基-4-雄烯-3-酮-17beta-羧酰胺合成路线 （共 15 条）
反应条件
in tetrahydrofuran 18 h; Heating; Yield given;
参考文献
Bhattacharya, A.; Williams, J.M.; Amato, J.S.; Dolling, U.-H.; Grabowski, E.J.J.
Synthetic Communications, 1990 , vol. 20, # 17 p. 2683 - 2690
反应条件
1: 85.13 percent / NaIO4, KMnO4, Na2CO3 / 2-methyl-propan-2-ol; H2O / 0.5 h / Heating 2: 89.47 percent / ammonium acetate / acetic acid / 4 h / Heating 3: 79.69 percent / 88percent HCOOH, K2CO3 / dimethylformamide / 6 h / Heating 4: 40.36 percent / <C6H5Se(O)>2O / chlorobenzene / 10 h / Heating View Scheme
参考文献
Xia, Peng; Yang, Zheng-Yu; Xia, Yi; Zhang, Hao-Bing; Zhang, Ke-Hua; Sun, Xun; Chen, Ying; Zheng, Yun-Qing
Heterocycles, 1998 , vol. 47, # 2 p. 703 - 716
反应条件
1: 85.13 percent / NaIO4, KMnO4, Na2CO3 / 2-methyl-propan-2-ol; H2O / 0.5 h / Heating 2: 89.47 percent / ammonium acetate / acetic acid / 4 h / Heating 3: 79.69 percent / 88percent HCOOH, K2CO3 / dimethylformamide / 6 h / Heating View Scheme
参考文献
Xia, Peng; Yang, Zheng-Yu; Xia, Yi; Zhang, Hao-Bing; Zhang, Ke-Hua; Sun, Xun; Chen, Ying; Zheng, Yun-Qing
Heterocycles, 1998 , vol. 47, # 2 p. 703 - 716
反应条件
1: 2,6-di-tert-butyl-4-methylpyridine / CH2Cl2 2: triethylamine / bis(triphenylphosphine)palladium(II) acetate / dimethylformamide / 760 Torr 3: K2CO3, H2O / methanol / Heating View Scheme
参考文献
Holt, Dennis A.; Levy, Mark A.; Oh, Hye-Ja; Erb, Jill M.; Heaslip, Julie I.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 3 p. 943 - 950
反应条件
1: 85.13 percent / NaIO4, KMnO4, Na2CO3 / 2-methyl-propan-2-ol; H2O / 0.5 h / Heating 2: 89.47 percent / ammonium acetate / acetic acid / 4 h / Heating View Scheme
参考文献
Xia, Peng; Yang, Zheng-Yu; Xia, Yi; Zhang, Hao-Bing; Zhang, Ke-Hua; Sun, Xun; Chen, Ying; Zheng, Yun-Qing
Heterocycles, 1998 , vol. 47, # 2 p. 703 - 716
