hydrogen; palladium dihydroxide in methanol 3 h; Ambient temperature;

<b>Multi-step reaction with 7 steps<br /> </b>1: 83 percent / NaH₂PO₄, Na₂HPO₄, Na(CN)BH₃ / H₂O / 24 h / Ambient temperature<br />2: 85 percent / Et₃N / tetrahydrofuran / 2 h / Heating<br />3: 92 percent / pyridine, tosyl chloride / CH₂Cl₂ / 24 h / Ambient temperature<br />4: 94 percent / LiAlH₄ / tetrahydrofuran / 1) -78 deg C, 90 min 2) -50 deg C 4 h<br />5: 97 percent / Et₃N / tetrahydrofuran / 1 h / Ambient temperature<br />6: 1) CuI / 1) Et₂O, -60 deg C 2) Et₂O, to -20 deg C, 2 h<br />7: 91 percent / conc. aq. HCl / 3 h / 80 &deg;C<br /> <br /> &nbsp;