2-(2-(溴甲基)苯基)-2H-1,2,3-噻唑合成路线 （共 2 条）
反应条件
phosphorus tribromide in tetrahydrofuran T=70°C; 0.333333 h;
参考文献
NOVARTIS AG; BADIGER, Sangamesh; BEHNKE, Dirk; BETSCHART, Claudia; COTESTA, Simona; HINTERMANN, Samuel; OFNER, Silvio; PANDIT, Chetan; ROY, Bernard Lucien
Patent: WO2012/55888 A1, 2012 ;
Location in patent: Page/Page column 120 ;
WO 2012/055888 A1
反应条件
1: caesium carbonate; copper(l) iodide; trans-N,N'-dimethylcyclohexane-1,2-diamine / N,N-dimethyl-formamide / 0.42 h / 120 - 160 °C / microwave 2: phosphorus tribromide / tetrahydrofuran / 0.33 h / 70 °C View Scheme
参考文献
NOVARTIS AG; BADIGER, Sangamesh; BEHNKE, Dirk; BETSCHART, Claudia; COTESTA, Simona; HINTERMANN, Samuel; OFNER, Silvio; PANDIT, Chetan; ROY, Bernard Lucien
Patent: WO2012/55888 A1, 2012 ;
WO 2012/055888 A1
