1-甲基-4-硝基吡咯-2-羧酸合成路线 （共 25 条）
反应条件
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=60°C; 15 h;
参考文献
Buerli, Roland W.; Jones, Peter; McMinn, Dustin; Le, Quan; Duan, Jian-Xin; Kaizerman, Jacob A.; Difuntorum, Stacey; Moser, Heinz E.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 5 p. 1259 - 1263
反应条件
1: SOCl2 / tetrahydrofuran / 0.08 h / Heating
2: 7.22 g / Huenig's base / tetrahydrofuran / -20 - 20 °C
3: H2 / Pd/C / methanol
View Scheme
参考文献
Parrick, John; Porssa, Manuchehr; Jenkins, Terence C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 22 p. 2681 - 2686
反应条件
hydrogenchloride; palladium monocarbide in 1,4-dioxane
参考文献
Caldarelli, Francesco; Ceriani, Lucio; Candiani, Ilaria
Patent: US2004/77550 A1, 2004 ;
反应条件
palladium on activated charcoal; ethanol
Hydrogenation;
参考文献
Ji, Zheng; Wang, Hui-Kang; Bastow, Kenneth F.; Zhu, Xiao-Kang; Cho, Sung Jin; Cheng, Yung-Chi; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 5 p. 607 - 612
反应条件
trichlorophosphate
0.5 h; Heating;
参考文献
Firoozi; Javidnia; Kamali; Fooladi; Foroumadi; Shafiee
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 1 p. 123 - 128
