3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
1: diethyl ether; benzene
2: K2S2O7 / 220 °C
View Scheme
参考文献
v. Wessely et al.
Monatshefte fuer Chemie, 1941 , vol. 73, p. 127,158
反应条件
manganese (II) chloride in tetrahydrofuran
T=0°C; 0.5 h;
参考文献
Zhang, Line; Ang, Gim Yean; Chiba, Shunsuke
Organic Letters, 2010 , vol. 12, # 16 p. 3682 - 3685
反应条件
triphenylphosphine in tetrahydrofuran; water
参考文献
Great Lakes Chemical Konstanz GmbH
Patent: US6121480 A1, 2000 ;
反应条件
1: in diethyl ether
T=-78 - 20°C; 12 h;
2: With ammonium chloride in diethyl ether; water
T=-78°C;
参考文献
PFIZER INC.
Patent: WO2006/18725 A1, 2006 ;
Location in patent: Page/Page column 155-156 ;
WO 2006/018725 A1
反应条件
2: 1.) Cp2ZrCl(H) / 2.) (Ph3P)2Pd(O)
View Scheme
参考文献
Crombie, Leslie; Horsham, Mark A.; Blade, Robert J.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4879 - 4882
反应条件
dichloro bis(acetonitrile) palladium(II); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in tetrahydrofuran
T=20°C; Kumada-Corriu reaction; 14 h; Inert atmosphere;
参考文献
Lopez-Perez, Ana; Adrio, Javier; Carretero, Juan C.
Organic Letters, 2009 , vol. 11, # 23 p. 5514 - 5517
反应条件
bis(acetylacetonate)nickel(II); triphenylphosphine in tetrahydrofuran
T=20°C; Inert atmosphere; regioselective reaction;
参考文献
Li, Qinghan; Gau, Hanmou
Synlett, 2012 , vol. 23, # 5 p. 747 - 750
反应条件
1: dilithium tetrachlorocuprate / tetrahydrofuran / 16 h / 0 - 20 °C
2: boron tribromide / dichloromethane / 16 h / 20 °C
View Scheme
参考文献
Yamaguchi, Yusuke; Okada, Yohei; Chiba, Kazuhiro
Journal of Organic Chemistry, 2013 , vol. 78, # 6 p. 2626 - 2638
反应条件
1: in tetrahydrofuran
T=-20°C; 2 h;
2: With sodium tetrahydroborate; iron(II) chloride in tetrahydrofuran; ethanol
T=20°C; 2 h; Further stages.;
参考文献
Sapountzis, Ioannis; Knochel, Paul
Journal of the American Chemical Society, 2002 , vol. 124, # 32 p. 9390 - 9391
反应条件
1: diethyl ether
2: formic acid
View Scheme
参考文献
Kovache
Annales de Chimie (Cachan, France), 1918 , vol. <9> 10, p. 200
