3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
diethyl ether
Erhitzen des Reaktionsprodukts unter vermindertem Druck;
参考文献
Howell; Robertson
Journal of the Chemical Society, 1936 , p. 587
反应条件
1: tetrahydrofuran / 17 h
2: p-toluenesulphonic acid / toluene / 1 h / Heating
View Scheme
参考文献
Alcock, Nathaniel J.; Mann, Inderjit; Peach, Philip; Wills, Martin
Tetrahedron Asymmetry, 2002 , vol. 13, # 22 p. 2485 - 2490
反应条件
1: 4-methoxyphenyl magnesium bromide With C24H52Cl2O12P4Pd2 in tetrahydrofuran; 1,4-dioxane
T=20°C; Kumada-Corriu cross-coupling reaction; 0.0833333 h; Inert atmosphere;
2: 2-chlorophenol in tetrahydrofuran; 1,4-dioxane
T=110°C; Kumada-Corriu cross-coupling reaction; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Ackermann, Lutz; Kapdi, Anant R.; Fenner, Sabine; Kornhaab, Christoph; Schulzke, Carola
Chemistry - A European Journal, 2011 , vol. 17, # 10 p. 2965 - 2971
反应条件
in tetrahydrofuran
3 h; Inert atmosphereReflux;
参考文献
Chang, Mingxin; Li, Wei; Hou, Guohua; Zhang, Xumu
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 18 p. 3121 - 3125
反应条件
1: pyrrolidin-2-one With chloro-trimethyl-silane; triethylamine in diethyl ether
0.5 h; Heating;
2: 4-methoxyphenyl magnesium bromide in diethyl ether
3 h; Heating;
参考文献
Coindet, Cecile; Comel, Alain; Kirsch, Gilbert
Tetrahedron Letters, 2001 , vol. 42, # 35 p. 6101 - 6104
反应条件
diethyl ether; mercury dichloride; benzene
参考文献
Blicke; Smith
Journal of the American Chemical Society, 1929 , vol. 51, p. 3481
反应条件
Fe(acac)3 in tetrahydrofuran
T=25°C; 3 h; Inert atmosphere;
参考文献
Volla, Chandra M. R.; Markovic, Dean; Dubbaka, Srinivas Reddy; Vogel, Pierre
European Journal of Organic Chemistry, 2009 , # 36 p. 6281 - 6288
反应条件
copper(l) iodide in tetrahydrofuran
T=70°C; 1 h; Inert atmosphere; regioselective reaction;
参考文献
Li, Man-Bo; Tang, Xiang-Ling; Tian, Shi-Kai
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1980 - 1984
反应条件
in diethyl ether
Ambient temperature; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Lajis, Nordin Hj.; Khan, Mohammad Niyaz
Tetrahedron, 1992 , vol. 48, # 6 p. 1109 - 1114
反应条件
in tetrahydrofuran
T=20°C; 10 h;
参考文献
Agai, Bela; Proszenyak, Agnes; Tarkanyi, Gabor; Vida, Laszlo; Faigl, Ferenc
European Journal of Organic Chemistry, 2004 , # 17 p. 3623 - 3632
