3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
copper(l) iodide in tetrahydrofuran
T=70°C; 2 h; Inert atmosphere; regioselective reaction;
参考文献
Li, Man-Bo; Tang, Xiang-Ling; Tian, Shi-Kai
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1980 - 1984
反应条件
C76H88Cl2FeN8P4 in tetrahydrofuran
T=0°C; 1 h; Schlenk techniqueInert atmosphere;
参考文献
Kawamura, Shintaro; Nakamura, Masaharu
Chemistry Letters, 2013 , vol. 42, # 2 p. 183 - 185
反应条件
FeCl(THF)L1 in diethyl ether
T=20°C; 0.5 h; Schlenk techniqueInert atmosphere; Catalytic behavior;
参考文献
UNIVERSITY OF PRINCE EDWARD ISLAND; GENESIS GROUP INC.; SHAVER, Michael, P.; KOZAK, Christopher, M.
Patent: WO2013/53046 A1, 2013 ;
Location in patent: Paragraph 00282-00284 ;
反应条件
in tetrahydrofuran
T=-40°C; Grignard reaction;
参考文献
L'Hermite, Nathalie; Peyrat, Jean-Francois; Alami, Mouad; Brion, Jean-Daniel
Tetrahedron Letters, 2005 , vol. 46, # 52 p. 8987 - 8991
参考文献
Bietti, Massimo; Lanzalunga, Osvaldo
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2632 - 2638
反应条件
((C6H4)(PPh2)(NCHPhP(O)Ph2))NiCl in diethyl ether
T=25°C; Kumada cross-coupling; 12 h; Inert atmosphere;
参考文献
Liu, Ning; Wang, Zhong-Xia
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 10031 - 10038
反应条件
1: diethyl ether / 20 °C
2: aq. HCl
3: DDQ / CH2Cl2 / 0.25 h / 20 °C
View Scheme
参考文献
Baddar; El-Assal
Journal of the Chemical Society, 1948 , p. 1267,1269
反应条件
1: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=-20°C; 0.166667 h;
2: bromobenzoic acid ethyl ester With para-fluorostyrene; tetra-(n-butyl)ammonium iodide; cobalt(II) 2,4-pentanedionate in tetrahydrofuran; ethylene glycol dimethyl ether
T=80°C; 0.25 h;
参考文献
Korn, Tobias J.; Schade, Matthias A.; Cheemala, Murthy N.; Wirth, Stefan; Guevara, Simon A.; Cahiez, Gerard; Knochel, Paul
Synthesis, 2006 , # 21 p. 3547 - 3574
反应条件
1: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=-20°C; 0.166667 h;
2: ethyl 2-fluoro-benzoate With N,N'-dimethyl-N,N'-propyleneurea; para-fluorostyrene; tetra-(n-butyl)ammonium iodide; cobalt(II) 2,4-pentanedionate in tetrahydrofuran; ethylene glycol dimethyl ether
T=80°C; 0.25 h;
参考文献
Korn, Tobias J.; Schade, Matthias A.; Cheemala, Murthy N.; Wirth, Stefan; Guevara, Simon A.; Cahiez, Gerard; Knochel, Paul
Synthesis, 2006 , # 21 p. 3547 - 3574
反应条件
1: diethyl ether
2: zinc cyanide; hydrogen chloride; benzene / durch Zufuegen von Aluminiumchlorid und Erwaermen auf 50grad
View Scheme
参考文献
Gulland; Virden
Journal of the Chemical Society, 1928 , p. 931
