3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
1: diethyl ether
2: copper oxide-chromium oxide; ethanol / 250 °C / 308913 Torr / Hydrogenation
View Scheme
参考文献
Rogers et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 2991,2999
反应条件
1: diethyl ether / Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts mit K2S2O7 unter Stickstoff auf 220grad
2: glacial acetic acid; palladium/charcoal / Hydrogenation
View Scheme
参考文献
v. Wessely et al.
Monatshefte fuer Chemie, 1941 , vol. 73, p. 127,158
反应条件
copper(l) iodide in tetrahydrofuran
T=70°C; 1 h; Inert atmosphere; regioselective reaction;
参考文献
Li, Man-Bo; Tang, Xiang-Ling; Tian, Shi-Kai
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 11-12 p. 1980 - 1984
反应条件
1: 4-methoxyphenyl magnesium bromide With PPh3 gold(I) chloro complex in tetrahydrofuran
T=-20 - 20°C; Inert atmosphere;
2: 1-iodo-2-methoxybenzene With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in acetonitrile
Inert atmosphere;
参考文献
Hashmi, A. Stephen K.; Lothschuetz, Christian; Doepp, Rene; Rudolph, Matthias; Ramamurthi, Tanuja D.; Rominger, Frank
Angewandte Chemie - International Edition, 2009 , vol. 48, # 44 p. 8243 - 8246
反应条件
Fe(acetylacetonate)2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one
T=20°C; Kumada coupling reaction; 0.5 h; Inert atmosphere;
参考文献
Qin, Jie; Chen, Fei; Ding, Ziyuan; He, Yan-Mei; Xu, Lijin; Fan, Qing-Hua
Organic Letters, 2011 , vol. 13, # 24 p. 6568 - 6571
反应条件
1: in diethyl ether
T=20°C; Grignard Reaction; 0.0416667 h;
2: With ammonium chloride in diethyl ether; water
T=20°C;
参考文献
Murai, Toshiaki; Morikawa, Kenta; Maruyama, Toshifumi
Chemistry - A European Journal, 2013 , vol. 19, # 39 p. 13112 - 13119
反应条件
diethyl ether
und Kochen des Reaktionsprodukts mit Ameisensaeure;
参考文献
Tiffeneau; Orechow
Bulletin de la Societe Chimique de France, 1923 , vol. <4> 33, p. 1837
反应条件
1: (i), (ii) oxalic acid
2: K2Cr2O7, H2SO4
View Scheme
参考文献
Flammang; Wermuth
European Journal of Medicinal Chemistry, 1976 , vol. 11, # 1 p. 83 - 88
反应条件
1.1: 73 percent / diethyl ether / 0 - 20 °C
2.1: TBAF / tetrahydrofuran
2.2: 90 percent / TBAF; (t-Bu)3P / [(allyl)PdCl]2 / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Denmark, Scott E.; Wu, Zhicai
Organic Letters, 1999 , vol. 1, # 9 p. 1495 - 1498
参考文献
Orechow; Tiffeneau
Bulletin de la Societe Chimique de France, 1921 , vol. <4>29, p. 452
