3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
1.1: tetrahydrofuran / 8 h / 0 °C / |Reflux
1.2: |Reflux
2.1: potassium carbonate; palladium diacetate; 2,2,2-trimethylacetic acid / N,N-dimethyl acetamide / 12 h / 160 °C / |Inert atmosphere
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参考文献
Guo, Lei; Zhang, Fengying; Hu, Weimin; Li, Lei; Jia, Yanxing
Chemical Communications, 2014 , vol. 50, # 25 p. 3299 - 3302
反应条件
1: diethyl ether; TeBr2 / Zersetzung mit Wasser und Erhitzen des Reaktionsproduktes mit Kupferpulver auf 275grad im CO2-Strom
2: bromine / Behandeln des entstandenen Dibromids mit verd. Natronlauge
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参考文献
Lederer
Chemische Berichte, 1916 , vol. 49, p. 1077
Chemische Berichte, 1920 , vol. 53, p. 714
反应条件
in diethyl ether
refluxing, 12 h;;
参考文献
Gmelin Handbook: Sn: Org.Verb.2, 1.1.2.15.7, page 408 - 418
参考文献
Gilman; Rosenberg
Journal of Organic Chemistry, 1953 , vol. 18, p. 680,682
反应条件
1: 92 percent / tetrahydrofuran / 0.5 h / 0 °C
2: 82 percent / tetrahydrofuran; toluene / 0.5 h / 0 °C
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参考文献
Knapp, Kolja M.; Goldfuss, Bernd; Knochel, Paul
Chemistry - A European Journal, 2003 , vol. 9, # 21 p. 5259 - 5265
参考文献
Cristol; Harms
Journal of the American Chemical Society, 1949 , vol. 71, p. 2875,4167
参考文献
Shevtsova,O.N.; Yurkevich,A.M.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 348 - 352,345 - 348
反应条件
lithium chloride in tetrahydrofuran; toluene
T=110°C; 48 h; Inert atmosphere;
参考文献
Shirakawa, Eiji; Okura, Keisho; Uchiyama, Nanase; Murakami, Takuya; Hayashi, Tamio
Chemistry Letters, 2014 , vol. 43, # 6 p. 922 - 924
反应条件
Ni(PCy3)2Cl2; tri-cyclo-hexyl-phosphine in diethyl ether
T=20°C; Kumada coupling; 2 h; Inert atmosphere;
参考文献
Guan, Bing-Tao; Lu, Xing-Yu; Zheng, Yang; Yu, Da-Gang; Wu, Tong; Li, Kun-N; Li, Bi-Jie; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 2 p. 396 - 399
反应条件
1: 4-methoxyphenyl magnesium bromide With C24H52Cl2O12P4Pd2 in tetrahydrofuran; 1,4-dioxane
T=20°C; Kumada-Corriu cross-coupling reaction; 0.0833333 h; Inert atmosphere;
2: C10H7-2-OTs in tetrahydrofuran; 1,4-dioxane
T=80°C; Kumada-Corriu cross-coupling reaction; 24 h; Inert atmosphere;
参考文献
Ackermann, Lutz; Kapdi, Anant R.; Fenner, Sabine; Kornhaab, Christoph; Schulzke, Carola
Chemistry - A European Journal, 2011 , vol. 17, # 10 p. 2965 - 2971
