3-甲基-CBS-氧硼啶合成路线 （共 731 条）
反应条件
2: HCl, CaCl2 / benzene
View Scheme
参考文献
Ward, Sarah; Messier, Tammy; Lukeman, Matthew
Canadian Journal of Chemistry, 2010 , vol. 88, # 6 p. 493 - 499
反应条件
oxygen; lithium chloride; manganese (II) chloride in tetrahydrofuran
T=-20°C; 1 h; Inert atmosphere; chemoselective reaction;
参考文献
Cahiez, Gerard; Duplais, Christophe; Buendia, Julien
Angewandte Chemie, International Edition, 2009 , vol. 48, # 36 p. 6731 - 6734
反应条件
1: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=-20°C; 0.166667 h;
2: ethyl 5-bromo-2-furancarboxylate With N,N'-dimethyl-N,N'-propyleneurea; para-fluorostyrene; tetra-(n-butyl)ammonium iodide; cobalt(II) 2,4-pentanedionate in tetrahydrofuran; ethylene glycol dimethyl ether
T=80°C; 8 h; Further stages.;
参考文献
Korn, Tobias J.; Schade, Matthias A.; Cheemala, Murthy N.; Wirth, Stefan; Guevara, Simon A.; Cahiez, Gerard; Knochel, Paul
Synthesis, 2006 , # 21 p. 3547 - 3574
反应条件
1-ethyl-2-pyrrolidinone; 4-(N,N-dimethlyamino)pyridine; phosphonic acid diethyl ester; nickel dichloride; zinc dibromide in tetrahydrofuran
T=20°C; 1 h;
参考文献
knochel, Paul; Gavriushin, Andrei; Kofink, Christiane Charlotte; Manolikakes, Georg
Patent: US2010/184977 A1, 2010 ;
Location in patent: Page/Page column 4 ;
反应条件
1: diethyl ether
View Scheme
参考文献
Tiffeneau; Levy; Weill
Bulletin de la Societe Chimique de France, 1931 , vol. <4> 49, p. 1709,1719
反应条件
2: basic. copper carbonate / 260 °C
View Scheme
参考文献
Sandin et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 3817
反应条件
diethyl ether
und Behandeln des Reaktionsprodukts mit verd. Salzsaeure.;
参考文献
Lee et al.
Journal of Organic Chemistry, 1947 , vol. 12, p. 885,892
反应条件
N,N,N',N,-tetramethylethylenediamine; iron(III) chloride in tetrahydrofuran
T=25°C; 0.5 h;
参考文献
Japan Science and Technology Agency
Patent: EP1724248 A1, 2006 ;
Location in patent: Page/Page column 20-22 ;
反应条件
1: 1-bromocyclohexane With [Fe(C2H4)4][Li(tmeda)]2 in tetrahydrofuran
T=-20°C;
2: 4-methoxyphenyl magnesium bromide in tetrahydrofuran; diethyl ether
T=-20°C; Further stages.;
参考文献
Fuerstner, Alois; Martin, Ruben; Krause, Helga; Seidel, Guenter; Goddard, Richard; Lehmann, Christian W.
Journal of the American Chemical Society, 2008 , vol. 130, # 27 p. 8773 - 8787
反应条件
anhydrous iron chloride; Ipr.HCl in tetrahydrofuran
T=0 - 40°C; 1.66667 h;
参考文献
Ghorai, Sujit K.; Jin, Masayoshi; Hatakeyama, Takuji; Nakamura, Masaharu
Organic Letters, 2012 , vol. 14, # 4 p. 1066 - 1069
