1: 29 percent / pyridine / 6 h / 60 °C 2: 47 percent / H2 / 10percent Pd/C / ethanol; H2O / 20 h / 760 Torr 3: sodium methoxide / methanol / 0.17 h / Ambient temperature 4: 1.) sodium hydride / 1.) DMF, 0 deg C, 2.) DMF, RT, 30 min View Scheme