6-甲氧基吲哚-1,3-二羧酸-1-苄基-3-甲酯合成路线 （共 8 条）
反应条件
4-methyl-morpholine in dichloromethane 1) r.t to 40 deg C 2) 1 h;
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
1: Zn, NH4Cl / ethanol; H2O 2: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 3: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h View Scheme
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
1: K2CO3 / diethyl ether; H2O / 1 h / 0 °C 2: 66 percent / N-methylmorpholine / CH2Cl2 / 1) r.t to 40 deg C 2) 1 h View Scheme
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 3: ethanol / 2 h / Heating 4: KOH / ethanol; H2O / 10 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr 2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C 3: ethanol / 2 h / Heating View Scheme
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
1: 100 percent / H2 / 10percent Pd-C / ethyl acetate / 760 Torr
2: 434 mg / DIBAL / tetrahydrofuran / 0.5 h / -78 °C
3: ethanol / 2 h / Heating
4: KOH / ethanol; H2O / 10 h / Heating
5: camphor-10-sulfonic acid / 12 h / Ambient temperature
View Scheme
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
P=760 Torr;
参考文献
Toyota, Masahiro; Fukumoto, Keiichiro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 5 p. 547 - 552
