1-苄基-3-羟基甲基-1H-吲唑合成路线 （共 12 条）
反应条件
1.1: isopropylmagnesium chloride / tetrahydrofuran / 2 h / -10 °C / Inert atmosphere 1.2: 0 °C 2.1: sodium bis(2-methoxyethoxy)aluminium dihydride / toluene / 0.25 h / 20 °C / Inert atmosphere View Scheme
参考文献
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.; CARACCIOLO TORCHIAROLO, Giuliano; IACOANGELI, Tommaso; FURLOTTI, Guido
Patent: WO2011/15501 A1, 2011 ;
Title/Abstract Full Text Show Details
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.; CARACCIOLO TORCHIAROLO, Giuliano; IACOANGELI, Tommaso; FURLOTTI, Guido
Patent: WO2011/15502 A1, 2011 ;
反应条件
1.1: hydrogenchloride / toluene; water / 2 h / 90 °C 2.1: sodium hydride / N,N-dimethyl-formamide; toluene / 1.5 h / Inert atmosphere 2.2: 10 h / 90 °C 3.1: sodium hydroxide / 3 h / Reflux View Scheme
参考文献
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.; CARACCIOLO TORCHIAROLO, Giuliano; IACOANGELI, Tommaso; FURLOTTI, Guido
Patent: WO2011/15502 A1, 2011 ;
