2-苄基-1,3,4-噁二唑合成路线 （共 11 条）
反应条件
Nafion(R)NR50 T=80°C; 0.166667 h; microwave irradiation;
参考文献
Polshettiwar, Vivek; Varma, Rajender S.
Tetrahedron Letters, 2008 , vol. 49, # 5 p. 879 - 883
反应条件
acetic acid T=145°C; 15 h;
参考文献
Kudelko, Agnieszka
Tetrahedron, 2011 , vol. 67, # 44 p. 8502 - 8508
反应条件
acetic acid 24 h; Reflux;
参考文献
Kudelko, Agnieszka
Tetrahedron, 2012 , vol. 68, # 18 p. 3616 - 3625
反应条件
toluene-4-sulfonic acid T=80 - 120°C;
参考文献
Ohmoto; Yamamoto; Okuma; Horiuchi; Imanishi; Odagaki; Kawabata; Sekioka; Hirota; Matsuoka; Nakai; Toda; Cheronis; Spruce; Gyorkos; Wieczorek
Journal of Medicinal Chemistry, 2001 , vol. 44, # 8 p. 1268 - 1285
反应条件
1: chlorotrimethylsilane / 5 h / 20 °C 2: hydrazine hydrate / 28 h / Heating 3: p-toluenesulfonic acid monohydrate / 80 - 120 °C View Scheme
参考文献
Ohmoto; Yamamoto; Okuma; Horiuchi; Imanishi; Odagaki; Kawabata; Sekioka; Hirota; Matsuoka; Nakai; Toda; Cheronis; Spruce; Gyorkos; Wieczorek
Journal of Medicinal Chemistry, 2001 , vol. 44, # 8 p. 1268 - 1285
反应条件
1: hydrazine hydrate / 28 h / Heating 2: p-toluenesulfonic acid monohydrate / 80 - 120 °C View Scheme
参考文献
Ohmoto; Yamamoto; Okuma; Horiuchi; Imanishi; Odagaki; Kawabata; Sekioka; Hirota; Matsuoka; Nakai; Toda; Cheronis; Spruce; Gyorkos; Wieczorek
Journal of Medicinal Chemistry, 2001 , vol. 44, # 8 p. 1268 - 1285
反应条件
1: hydrazine hydrate / methanol / 24 h / 20 °C 2: acetic acid / anhydrous xylene / 13 h / 145 °C View Scheme
参考文献
Kudelko, Agnieszka
Tetrahedron, 2011 , vol. 67, # 44 p. 8502 - 8508
反应条件
1: NaHS monohydrate / water / 14 h / -5 °C / Heating 2: sulfuric acid / 6 h / Reflux 3: hydrazine hydrate / methanol / 24 h / -5 - 0 °C 4: acetic acid / 24 h / Reflux View Scheme
参考文献
Kudelko, Agnieszka
Tetrahedron, 2012 , vol. 68, # 18 p. 3616 - 3625
反应条件
1: hydrazine hydrate / methanol / 24 h / -5 - 0 °C 2: acetic acid / 24 h / Reflux View Scheme
参考文献
Kudelko, Agnieszka
Tetrahedron, 2012 , vol. 68, # 18 p. 3616 - 3625
反应条件
1: sulfuric acid; hydrogen bromide / 3 h / Reflux 2: NaHS monohydrate / water / 14 h / -5 °C / Heating 3: sulfuric acid / 6 h / Reflux 4: hydrazine hydrate / methanol / 24 h / -5 - 0 °C 5: acetic acid / 24 h / Reflux View Scheme
参考文献
Kudelko, Agnieszka
Tetrahedron, 2012 , vol. 68, # 18 p. 3616 - 3625
