1: With sodium azide; tetrabutylammomium bromide in toluene Reflux; 2: With triphenylphosphine in toluene 24 h; Reflux;

1.1: potassium carbonate / N,N-dimethyl-formamide / 40 h / 100 °C / Inert atmosphere 2.1: nitric acid; acetic acid / dichloromethane / 41 h / 10 - 20 °C 3.1: sodium azide; tetrabutylammomium bromide / toluene / Reflux 3.2: 24 h / Reflux View Scheme

1.1: potassium carbonate / N,N-dimethyl-formamide / 40 h / 100 °C / Inert atmosphere 2.1: nitric acid; acetic acid / dichloromethane / 41 h / 10 - 20 °C 3.1: sodium azide; tetrabutylammomium bromide / toluene / Reflux 3.2: 24 h / Reflux View Scheme

1.1: nitric acid; acetic acid / dichloromethane / 41 h / 10 - 20 °C 2.1: sodium azide; tetrabutylammomium bromide / toluene / Reflux 2.2: 24 h / Reflux View Scheme

bromine; acetic acid in dichloromethane T=20°C; 72 h; Darkness;