131543-46-9合成路线 （共 480 条）
反应条件
1: ethane-1,2-dial With phosphorous pentoxide; water T=20°C; 0.0833333 h; 2: monomethylthiourea T=20°C; 0.166667 h;
参考文献
Baccolini, Graziano; Boga, Carla; Delpivo, Camilla; Micheletti, Gabriele
Tetrahedron Letters, 2011 , vol. 52, # 14 p. 1713 - 1717
反应条件
sodium hydroxide in methanol; water T=-35 - 20°C;
参考文献
Gerritsma, David A.; Brindle, Ian D.; Jones, Timothy R.B.; Capretta, Alfredo
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, # 3 p. 243 - 253
反应条件
in methanol 3 h; Heating;
参考文献
Sauer, Juergen; Heldmann, Dieter K.; Pabst, Gunther R.
European Journal of Organic Chemistry, 1999 , # 1 p. 313 - 321
反应条件
in water T=60 - 100°C;
参考文献
Shintou, Taichi; Ikeuchi, Fumiaki; Kuwabara, Hirokazu; Umihara, Ken; Itoh, Isamu
Chemistry Letters, 2005 , vol. 34, # 6 p. 836 - 837
反应条件
in ethanol; water T=110°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD; XI, Ning; WANG, Ruyong; WANG, Liang
Patent: WO2014/89324 A1, 2014 ;
Location in patent: Paragraph 0302 ;
参考文献
Ferruti,P. et al.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2984 - 2985
反应条件
ammonia; acetic acid T=70°C; 24 h;
参考文献
Vogel, Carola S.; Heinemann, Frank W.; Khusniyarov, Marat M.; Meyer, Karsten
Inorganica Chimica Acta, 2010 , vol. 364, # 1 p. 226 - 237
参考文献
Murase
Bulletin of the Chemical Society of Japan, 1959 , vol. 32, p. 827,829, 831
反应条件
acetic acid in methanol; water
参考文献
Gallucci, Robert R.
Journal of Chemical & Engineering Data, 1982 , vol. 27, # 2 p. 217 - 219
反应条件
in water T=90°C; Hinsberg condensation; 1.5 h;
参考文献
Hui, Xu; Schmidt, Fanny; Fakhfakh, Mohammed Akram; Franck, Xavier; Figadere, Bruno
Heterocycles, 2007 , vol. 72, p. 353 - 361
