131543-46-9合成路线 （共 480 条）
参考文献
DEGUSSA AG
Patent: US2004/186304 A1, 2004 ;
Location in patent: Page 3 ;
反应条件
ammonium hydroxide in ethanol; water
T=0 - 20°C;
参考文献
Chen, Jianjun; Wang, Zhao; Li, Chien-Ming; Lu, Yan; Vaddady, Pavan K.; Meibohm, Bernd; Dalton, James T.; Miller, Duane D.; Li, Wei
Journal of Medicinal Chemistry, 2010 , vol. 53, # 20 p. 7414 - 7427
反应条件
ammonium hydroxide in water
T=10°C;
参考文献
Huang, Zilin; Jin, Jeff; Machajewski, Timothy; Antonios-McCrea, William R.; McKenna, Maureen; Poon, Daniel; Renhowe, Paul A.; Sendzik, Martin; Shafer, Cynthia; Smith, Aaron; Xu, Yongjin; Zhang, Qiong; Chen, Zheng
Patent: US2013/210818 A1, 2013 ;
Location in patent: Paragraph 0332 ;
反应条件
toluene-4-sulfonic acid
参考文献
Kliegman,J.M.; Barnes,R.K.
Journal of Organic Chemistry, 1973 , vol. 38, p. 556 - 560
反应条件
hydrogenchloride in ethanol; water
参考文献
Klaubert, Dieter H.; Meisenheimer, Poncho; Unch, James
Patent: US2012/117667 A1, 2012 ;
参考文献
Reich; Hefle
Journal of Organic Chemistry, 1956 , vol. 21, p. 708
反应条件
in water; N,N-dimethyl-formamide
T=80°C; 8 h;
参考文献
Murray, Michael M.; Kaszynski, Piotr; Kaisaki, David A.; Chang, Wonghil; Dougherty, Dennis A.
Journal of the American Chemical Society, 1994 , vol. 116, # 18 p. 8152 - 8161
反应条件
acetic acid in water
T=110°C; 1 h;
参考文献
Begtrup, Mikael; Nytoft, Hans Peter
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 81 - 86
反应条件
sodium hydroxide
T=50°C; 2 h; pH 5;
参考文献
Kravchenko; Sigachev; Maksareva; Gazieva; Trunova; Lozhkin; Pivina; Il'in; Lyssenko; Nelyubina; Davankov; Lebedev; Makhova; Tartakovsky
Russian Chemical Bulletin, 2005 , vol. 54, # 3 p. 691 - 704
反应条件
in ethanol
1.) room temperature, 16 h, 2.) reflux, 1 h;
参考文献
Benson, Scott C.; Gross, Jonathan L.; Snyder, John K.
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3257 - 3269
