131543-46-9合成路线 （共 480 条）
反应条件
in ethanol; water
Heating;
参考文献
Torgashev, P. A.; Kazantseva, I. V.; Chupakhin, O. N.; Charushin, V. N.; Belik, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 8 p. 936 - 943
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , # 8 p. 1118 - 1125
反应条件
sodium hydroxide
pH 10.5;
参考文献
Evans et al.
Journal of the Chemical Society, 1956 , p. 4106,4111
反应条件
hydrogenchloride in ethanol; water
参考文献
Klaubert, Dieter H.; Meisenheimer, Poncho; Unch, James
Patent: US2012/117667 A1, 2012 ;
反应条件
T=50°C; Neat (no solvent);
参考文献
Ikhile, Monisola I.; Bala, Muhammad D.; Nyamori, Vincent O.
South African Journal of Chemistry, 2011 , vol. 64, p. 101 - 104
反应条件
T=50°C; Neat (no solvent);
参考文献
Ikhile, Monisola I.; Bala, Muhammad D.; Nyamori, Vincent O.
South African Journal of Chemistry, 2011 , vol. 64, p. 101 - 104
反应条件
in water
T=0 - 20°C; 11 h;
参考文献
Centre National de la Recherche Scientifique (C.N.R.S.); Commissariat a l'energie Atomique
Patent: US7312327 B2, 2007 ;
Location in patent: Page/Page column 12 ;
反应条件
1: With phosphoric acid in 1,4-dioxane; water
T=80°C; pH=2; 0.5 h;
2: With ammonium chloride in 1,4-dioxane; water
T=100°C; 3 h; Further stages.;
参考文献
Perry, Marc C.; Cui, Xiuhua; Powell, Mark T.; Hou, Duen-Ren; Reibenspies, Joseph H.; Burgess, Kevin
Journal of the American Chemical Society, 2003 , vol. 125, # 1 p. 113 - 123
反应条件
sodium carbonate in 1,4-dioxane; water
参考文献
Merck Sharp and Dohme Limited
Patent: US6080745 A1, 2000 ;
反应条件
sodium cyanoborohydride in water
0.5 h; pH 6;
参考文献
Temple, Carroll; Bennett, L. Lee; Rose, Jerry D.; Elliott, Robert D.; Montgomery, John A.; Mangum, John H.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 161 - 166
反应条件
in ethanol
2 h; Heating / reflux;
参考文献
Wyeth
Patent: EP1147083 B1, 2004 ;
Location in patent: Page 48 ;
EP 1147083 B1
