131543-46-9合成路线 （共 480 条）
反应条件
acetic acid in ethanol; water
T=100°C;
参考文献
JANSSEN PHARMACEUTICA, N.V.
Patent: WO2007/75567 A1, 2007 ;
Location in patent: Page/Page column 131 ;
WO 2007/075567 A1
反应条件
in ethanol; water
T=55 - 60°C; 1 h;
参考文献
Sato, Nobuhiro; Mizuno, Hajime
Journal of Chemical Research - Part S, 1997 , # 7 p. 250 - 251
反应条件
potassium tert-butylate; dimethyl sulfoxide
1.) 2 h, 2.) THF, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Wilcox, Charles F.; Farley, Eric N.
Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 351 - 356
反应条件
potassium tert-butylate; dimethyl sulfoxide
1.) 2 h, 2.) THF, 22 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Wilcox, Charles F.; Farley, Eric N.
Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 351 - 356
参考文献
Friedlaender; Risse
Chemische Berichte, 1914 , vol. 47, p. 1925
Full Text Show Details
Kalle and Co.
Patent: DE239916 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 10, p. 550
参考文献
Friedlaender; Risse
Chemische Berichte, 1914 , vol. 47, p. 1922
反应条件
in water
1 h; Heating;
参考文献
Chassonnery, Dominique; Chastrette, Francine; Chastrette, Maurice; Blanc, Alain; Mattioda, Georges
Bulletin de la Societe Chimique de France, 1994 , vol. 131, p. 188 - 199
反应条件
hydrogenchloride in water
T=-15°C; 2.5 h;
参考文献
Abel, Edward W.; Higgins, Kevin M.; Orrell, Keith G.; Sik, Vladimir; Curzon, Eirian H.; Howarth, Oliver W.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1985 , p. 2195 - 2202
反应条件
in water
1 h; Heating;
参考文献
Chassonnery, Dominique; Chastrette, Francine; Chastrette, Maurice; Blanc, Alain; Mattioda, Georges
Bulletin de la Societe Chimique de France, 1994 , vol. 131, p. 188 - 199
反应条件
hydrogenchloride in water
T=60°C; pH=3; 4 h;
参考文献
Cortial, Sylvie; Chaignon, Philippe; Sergent, Didier; Dezard, Sophie; Ouazzani, Jamal
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 76, p. 1 - 8
