2,4-二氯-5-氨基-6-甲基嘧啶合成路线 （共 3 条）
反应条件
ethanol; nickel Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 76, p. 1953
反应条件
hydrogen; magnesium oxide; palladium 10 on activated carbon in ethanol; water T=20°C; P=760.051 Torr;
参考文献
US2009/93472 A1, ;
Page/Page column 23-24 ;
US 20090093472 A1
反应条件
1: 23 g / HCl / ethanol; H2O / 3 h / Heating
2: 30 percent / acetic anhydride / 3 h / Heating
3: 76 percent / H2O; dimethylformamide / 3 h / 100 °C
4: 84 percent / Raney Ni, conc. HCl / ethanol / 4 h / Heating
5: 40 percent / NaH / tetrahydrofuran / Heating
View Scheme
参考文献
Tanji; Satoh; Higashino
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 227 - 229
