1-(2-甲氧基吡啶-3-基)乙酮合成路线 （共 6 条）
反应条件
1: in tetrahydrofuran; diethyl ether 1.5 h; Cooling with ice; 2: With ammonium chloride in tetrahydrofuran; diethyl ether; ethyl acetate
参考文献
EP2287173 A1, ;
Page/Page column 38 ;
反应条件
1: 1) butyllithium, di-isopropylamine / 1) THF, hexane, 0 deg C, 1 h 2) THF, -70 deg C, 3 h 2: 95 percent / chromic anhydride / acetone / 3 h / Ambient temperature 3: 1) MeOH, reflux, 7 h 2) hydrolysis View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 2409 - 2415
反应条件
1: 95 percent / chromic anhydride / acetone / 3 h / Ambient temperature 2: 1) MeOH, reflux, 7 h 2) hydrolysis View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 2409 - 2415
反应条件
1.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 6 h / Cooling with ice 1.2: 20 °C 2.1: diethyl ether; tetrahydrofuran / 1.5 h / Cooling with ice View Scheme
反应条件
Irradiation; Yield given;
参考文献
Tetrahedron Letters, , vol. 36, # 28 p. 5065 - 5068
反应条件
1) MeOH, reflux, 7 h 2) hydrolysis; Yield given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 9 p. 2409 - 2415
