pyridine hydrochloride T=220°C; 0.333333 h;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1) butyllithium, di-isopropylamine / 1) THF, hexane, 0 deg C, 1 h 2) THF, -70 deg C, 3 h<br />2: 81 percent / MnO₂ / toluene / Heating<br />3: 1) MeOH, reflux, 7 h 2) hydrolysis<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 81 percent / MnO₂ / toluene / Heating<br />2: 1) MeOH, reflux, 7 h 2) hydrolysis<br /> <br /> &nbsp;

&nbsp;1) MeOH, reflux, 7 h 2) hydrolysis;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1) butyllithium, di-isopropylamine / 1) THF, hexane, 0 deg C, 1 h 2) THF, -70 deg C, 3 h<br />2: 81 percent / MnO₂ / toluene / Heating<br />3: 1) MeOH, reflux, 7 h 2) hydrolysis<br /> <br /> &nbsp;