(三甲基硅基)甲基氯化镁合成路线 （共 130 条）
反应条件
copper(l) iodide in tetrahydrofuran
T=-40°C; 1.5 h;
参考文献
Fuerstner, Alois; Kollegger, Gerlinde; Weidmann, Hans
Journal of Organometallic Chemistry, 1991 , vol. 414, # 3 p. 295 - 305
参考文献
Lutsenko,I.F. et al.
Journal of Organometallic Chemistry, 1968 , vol. 11, p. 35 - 48
反应条件
1: trimethylsilyl-methylmagnesium chloride With zinc(II) iodide in diethyl ether
Addition; 6 h; Heating;
2: 2-(1-methyl-2-phenyl-ethyl)-[1,3]dioxolane in benzene
Grignard reaction; 8 h; Heating; Further stages.;
参考文献
Chiang, Chao-Cheng; Chen, Yu-Huei; Hsieh, Yu-Tsai; Luh, Tien-Yau
Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4694 - 4697
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=35°C; 15 h;
参考文献
Andreini, Bianca Patrizia; Carpita, Adriano; Rossi, Renzo; Scamuzzi, Barbara
Tetrahedron, 1989 , vol. 45, # 17 p. 5621 - 5640
反应条件
in not given
under Ar; Me3SiCH2Cl (3 equiv.) in THF or hexane or Et2O added slowly (15-30 min) to cooled (-78°C) soln. of InCl3 in THF; stirred for 30min; warmed to room temp.; according to H. C. Clark, A. L. Pickard, J. Organomet. Chem. 8 (1967) 427;
参考文献
Perez; Sestelo; Sarandeses
Journal of the American Chemical Society, 2001 , vol. 123, # 18 p. 4155 - 4160
反应条件
1.) Et2O, -60 deg C, 25 min, 2.) THF, -60 deg C to r.t.; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Mueller, Gerhard; Waldkircher, Martin; Winkler, Martin
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1994 , vol. 49, # 12 p. 1606 - 1614
反应条件
C12H18ClO2P2Rh in diethyl ether
T=22°C; Kumada coupling reaction; 0.0833333 h;
参考文献
Timpa, Samuel D.; Fafard, Claudia M.; Herbert, David E.; Ozerov, Oleg V.
Dalton Transactions, 2011 , vol. 40, # 20 p. 5426 - 5429
反应条件
sulfuric acid in tetrahydrofuran; diethyl ether
参考文献
Dainippon Pharmaceutical Company, Limited
Patent: US6555557 B1, 2003 ;
反应条件
in diethyl ether
under Ar Grignard reagent added dropwise to GaCl3-ether soln. over a period of 1 h, mixt. stirred for 24 h at room temp.; Et2O removed by vac. distn., product distd. from reaction mixt. at 120°C under high vac.; elem. anal.;
参考文献
Beachley, O. T. Jr.; Simmons, Randall G.
Inorganic Chemistry, 1980 , vol. 19, p. 1021 - 1025
反应条件
copper (I) cyanide; lithium chloride in diethyl ether
T=20°C; 18 h;
参考文献
Mentink, Gertjan; Van Maarseveen, Jan H.; Hiemstra, Henk
Organic Letters, 2002 , vol. 4, # 20 p. 3497 - 3500
