6-溴-5-羟基-1-甲基-2-(苯基硫甲基)吲哚-3-甲酸乙酯合成路线 （共 6 条）
反应条件
potassium hydroxide in methanol 3 h; Ambient temperature;
参考文献
Trofimov, F.A.; Tsyshkova, N.G.; Zotova, S.A.; Grinev, A.N.
Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 1 p. 75 - 76
Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 1 p. 70 - 71
反应条件
1H-imidazole in xylene Heating;
参考文献
Zotova, S. A.; Shvedov, V. I.
Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 2 p. 103 - 106
Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 2 p. 22 - 24
反应条件
1: 87 percent / Br2 / CCl4 / 2 h / Heating 2: 96.4 percent / KOH / methanol / 3 h / Ambient temperature View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 27, # 1 p. 75 - 76
Khimiko-Farmatsevticheskii Zhurnal, , vol. 27, # 1 p. 70 - 71
反应条件
acetic acid in water T=65 - 75°C; 0.5 h;
参考文献
Pharmaceutical Chemistry Journal, , vol. 27, # 1 p. 75 - 76
Khimiko-Farmatsevticheskii Zhurnal, , vol. 27, # 1 p. 70 - 71
反应条件
potassium hydroxide; acetic acid; dimethyl amine
反应条件
in 1,4-dioxane 3 h; Heating;
参考文献
Pharmaceutical Chemistry Journal, , vol. 27, # 1 p. 75 - 76
Khimiko-Farmatsevticheskii Zhurnal, , vol. 27, # 1 p. 70 - 71
