1: 85 percent / KI, K2CO3 / acetone / 96 h / Heating 2: 94 percent / 3.3 M aq. NaOH / 1,2-dimethoxy-ethane / 9 h / Heating View Scheme

1: 85 percent / KI, K2CO3 / acetone / 96 h / Heating 2: 94 percent / 3.3 M aq. NaOH / 1,2-dimethoxy-ethane / 9 h / Heating View Scheme

1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 85 °C / Inert atmosphere 2: potassium hydroxide; water / tetrahydrofuran / 20 °C View Scheme

1: TAM(COOH)2(Bn)2 With oxalyl dichloride in DMF (N,N-dimethyl-formamide); toluene 24 h; 2: 2-mercapto-4,5-dihydro-thiazole With triethylamine in tetrahydrofuran T=-35°C; 2 h;