4,5-二氯异噻唑-3-羧酸合成路线 (共 3 条)
参考文献
Kaberdia, R. V.; Potkin, V. I.; Ol'dekop, Yu. A.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 7.2 p. 1347 - 1351
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 7 p. 1560 - 1566
反应条件
thionyl chloride in tetrachloromethane 16 h; Heating;
参考文献
Potkin; Petkevich; Kletskov; Dikusar; Zubenko; Zhukovskaya; Kazbanov; Pashkevich
Russian Journal of Organic Chemistry, 2013 , vol. 49, # 10 p. 1523 - 1533
Zh. Org. Khim., 2013 , vol. 49, # 10 p. 1543 - 1553,11
反应条件
in methanol; hexane; toluene T=20°C; 0.5 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; PINTO, Donald J.; CORTE, James R.; GILLIGAN, Paul J.; FANG, Tianan; SMITH II, Leon M.; WANG, Yufeng; YANG, Wu; EWING, William R.
Patent: WO2013/22818 A1, 2013 ;
Location in patent: Paragraph 00429 ;
WO 2013/022818 A1