2-[5-(4-甲氧基苯甲酰基)-10-甲基-4H-吡咯并[1,2-b][1,2,5]苯并三氮杂卓-4-基]乙酸合成路线 （共 3 条）
反应条件
potassium hydroxide in ethanol 18 h; Ambient temperature;
参考文献
Stefancich; Artico; Silvestri; Prosini; Pantaleoni; Giorgi; Palumbo
Farmaco, 1990 , vol. 45, # 7-8 p. 817 - 831
反应条件
1: 75 percent / tetrahydrofuran / 15 h / Ambient temperature 2: 74 percent / POCl3 / CH2Cl2 / 20 h / Heating 3: 90 percent / NaBH3CN, HCl / ethanol; tetrahydrofuran / 20 h / Ambient temperature 4: 80 percent / Et3N / tetrahydrofuran / 72 h / Heating 5: 87 percent / 1N aq. KOH / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Stefancich; Artico; Silvestri; Prosini; Pantaleoni; Giorgi; Palumbo
Farmaco, 1990 , vol. 45, # 7-8 p. 817 - 831
反应条件
1: 90 percent / NaBH3CN, HCl / ethanol; tetrahydrofuran / 20 h / Ambient temperature 2: 80 percent / Et3N / tetrahydrofuran / 72 h / Heating 3: 87 percent / 1N aq. KOH / ethanol / 18 h / Ambient temperature View Scheme
参考文献
Stefancich; Artico; Silvestri; Prosini; Pantaleoni; Giorgi; Palumbo
Farmaco, 1990 , vol. 45, # 7-8 p. 817 - 831
