2-(2-氯苯基)-噻唑-4-羧酸乙酯合成路线 （共 6 条）
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol diethyl ether; water T=80°C; 3 h;
参考文献
WO2004/2977 A1, ;
Page 23 ;
WO 2004/002977 A1
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 20 p. 3491 - 3495
反应条件
in ethanol 8 h; Reflux;
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 67, # 7 p. 747 - 758
反应条件
potassium hydroxide T=50°C;
参考文献
Larsen, Scott D.; Stachew, Carl F.; Clare, Paula M.; Cubbage, Jerry W.; Leach, Karen L.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 20 p. 3491 - 3495
反应条件
diisobutylaluminium hydride in dichloromethane; toluene
T=-78°C; 1 h;
参考文献
PHARMACIA and UPJOHN COMPANY; FINZEL, Barry, C.
Patent: WO2004/2977 A1, 2004 ;
Location in patent: Page 23-24 ;
WO 2004/002977 A1
反应条件
diisobutylaluminium hydride in dichloromethane; toluene
T=-78°C; 1 h;
参考文献
PHARMACIA and UPJOHN COMPANY; FINZEL, Barry, C.
Patent: WO2004/2977 A1, 2004 ;
Location in patent: Page 23-24 ;
WO 2004/002977 A1
