2-氯-9H-氧杂蒽-9-酮合成路线 （共 18 条）
反应条件
sulfuric acid
T=100°C;
参考文献
Ullmann; Wagner
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 366
Justus Liebigs Annalen der Chemie, 1909 , vol. 371, p. 388
反应条件
1: 80 percent / pyrrolidine / toluene / 1.) RT, 1 h, 2.) reflux, 8 h
2: 94 percent / thallium(III) p-tosylate / acetonitrile / 1 h / Heating
3: 80 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / dioxane / 18 h / Heating
View Scheme
参考文献
Singh, Om V.; George, Varughese; Kapil, Randhir S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 10 p. 856 - 864
反应条件
1: 80 percent / pyrrolidine / toluene / 1.) RT, 1 h, 2.) reflux, 8 h
2: 94 percent / thallium(III) p-tosylate / acetonitrile / 1 h / Heating
3: 80 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / dioxane / 18 h / Heating
View Scheme
参考文献
Singh, Om V.; George, Varughese; Kapil, Randhir S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 10 p. 856 - 864
反应条件
1: KMnO4
2: sodium methylate / Behandeln des Reaktionsprodukts mit Kupfer auf 180grad
3: concentrated sulfuric acid / 100 °C
View Scheme
参考文献
Ullmann; Wagner
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 366
Justus Liebigs Annalen der Chemie, 1909 , vol. 371, p. 388
反应条件
1: sodium methylate / Behandeln des Reaktionsprodukts mit Kupfer auf 180grad
2: concentrated sulfuric acid / 100 °C
View Scheme
参考文献
Ullmann; Wagner
Justus Liebigs Annalen der Chemie, 1907 , vol. 355, p. 366
Justus Liebigs Annalen der Chemie, 1909 , vol. 371, p. 388
参考文献
Dhar
Journal of the Chemical Society, 1920 , vol. 117, p. 1063
反应条件
1: 94.4 percent / NaOH, zinc dust, methanol / 4 h / Ambient temperature
2: HClO4 / diethyl ether / -78 °C
3: 70.6 percent / acetonitrile / Ambient temperature
4: 90 percent / NaOMe / tetrahydrofuran / 4 h / Ambient temperature; other phosphonate, var. aldehydes and ketones; other reagent
View Scheme
参考文献
Christie, Michael A.; Webb, Lee R.; Tickner, Ann M.
Journal of Organic Chemistry, 1982 , vol. 47, # 14 p. 2802 - 2804
反应条件
potassium hydroxide in tetrahydrofuran; water
参考文献
SmithKline Corporation
Patent: US4086350 A1, 1978 ;
