1H-苯并[d][1,3]噁嗪-2(4h)-酮合成路线 （共 19 条）
反应条件
potassium hydrogencarbonate in tetrahydrofuran; water T=7 - 17°C; 2 h;
参考文献
LONZA LTD; GRIFFITHS, Gareth-John; LORENZI, Miriam; WARM, Aleksander
Patent: WO2010/115640 A1, 2010 ;
Location in patent: Page/Page column 7 ;
反应条件
1: in tetrahydrofuran T=0°C; 0.166667 h; 2: With triethylamine in tetrahydrofuran T=0 - 20°C; 0.5 h;
参考文献
AGIOS PHARMACEUTICALS, INC.; SALITURO, Francesco, G.; SAUNDERS, Jeffrey, O.
Patent: WO2012/88314 A1, 2012 ;
Location in patent: Page/Page column 53-54 ;
WO 2012/088314 A1
反应条件
N-methyl-pyrrolidine; selenium in tetrahydrofuran T=15°C; P=735.5 Torr; 10 h;
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Murai, Shinji; Sonoda, Noboru
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 1793 - 1800
反应条件
selenium; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine in toluene T=150°C; P=22800 Torr; 7 h;
参考文献
Wang, Xiaofang; Ling, Gang; Xue, Yan; Lu, Shiwei
European Journal of Organic Chemistry, 2005 , # 8 p. 1675 - 1679
反应条件
bis-[(trifluoroacetoxy)iodo]benzene in N,N-dimethyl-formamide T=0°C; Hofmann rearrangement; 1 h;
参考文献
Hernandez, Eliud; Velez, Jessica M.; Vlaar, Cornelis P.
Tetrahedron Letters, 2007 , vol. 48, # 51 p. 8972 - 8975
反应条件
triethylamine in toluene
参考文献
Imperial Chemical Industries PLC; ICI Pharma
Patent: US5217969 A1, 1993 ;
US 5217969 A
反应条件
sodium hydroxide in chloroform T=20°C; 0.5 h;
参考文献
SABIC INNOVATIVE PLASTICS IP BV
Patent: US2010/113819 A1, 2010 ;
Location in patent: Page/Page column 9 ;
反应条件
triethylamine; palladium dichloride in N,N-dimethyl acetamide T=70°C; P=760.051 Torr; 24 h; Schlenk technique;
参考文献
Ren, Long; Jiao, Ning
Chemical Communications, 2014 , vol. 50, # 28 p. 3706 - 3709
反应条件
triethylamine in tetrahydrofuran
参考文献
OTSUKA PHARMACEUTICAL CO., LTD.
Patent: EP239129 B1, 1991 ;
反应条件
lithium borohydride in tetrahydrofuran 0.25 h;
参考文献
Narasimhan, Srinivasan
Heterocycles, 1982 , vol. 18, p. 131 - 135
