丙-2-烯基吡嗪-2-羧酸酯合成路线 (共 3 条)
反应条件
pyridine in dichloromethane
参考文献
The Research Foundation of State University of New York
Patent: US4962111 A1, 1990 ;
反应条件
pyridine in dichloromethane 1.) 0 deg C, 1 h, 2.) RT, overnight;
参考文献
Cynamon, Michael H.; Klemens, Sally P.; Chou, Tso-Sheng; Gimi, Rayomand H.; Welch, John T.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1212 - 1215
反应条件
1: 74 percent / thionyl chloride / benzene / 2 h / Heating 2: 58 percent / pyridine / CH2Cl2 / 1.) 0 deg C, 1 h, 2.) RT, overnight View Scheme
参考文献
Cynamon, Michael H.; Klemens, Sally P.; Chou, Tso-Sheng; Gimi, Rayomand H.; Welch, John T.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1212 - 1215